A UK cohort study of 7949 men and women employed during 1947-1984 in eight companies manufacturing glass-reinforced plastics involving high exposure to styrene
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چکیده
Three studies have suggested an association between leukaemia and Iymphomas and exposure to styrene. ln a mortality analysis of2904 US workers exposed to low or moderate levels of styrene (not exceeding 100 ppm (420 mgj m3)), six cases ofleukaemia (3.4 expected; standardized mortality ratio (SMR), 176) and seven cases of Iymphoma (5.3 expected; SMR, 132) were observed. When the incidence was analysed, seven cases of lymphatic leukaemia (1.6 expected), four cases of all other leukaemias (2.9 expected) and four cases of multiple myeloma (1.6 expected) were found. However, six of the leukaemia cases occurred
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Trends in Occupational Exposure to Styrene in the European Glass Fibre-Reinforced Plastics Industry
AIM This study presents temporal trends of styrene exposure for workers in the European glass fibre-reinforced plastics (GRP) industry during the period 1966-2002. METHODS Data of personal styrene exposure measurements were retrieved from reports, databases and peer-reviewed papers. Only sources with descriptive statistics of personal measurements were accepted. The styrene exposure data cove...
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Eight male workers from a glass reinforced plastics industry were experimentally exposed for 2 hours to 2.84 mmol/m3 (296 mg/m3) styrene during light physical exercise (50 W). About 63% of the amount supplied (4.6 mmol styrene) was taken up in the body. The arterial blood concentration of styrene reached a relatively stable level of 15 mumol/l at the end of exposure which was about 70% of the b...
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A cohort of 34,560 men and 6128 women employed in 660 European factories manufacturing reinforced plastic products, followed up originally to assess the risk of cancer, was used to assess the risk of non-malignant respiratory diseases associated with exposure to styrene. Mortality from pneumonia was associated with intensity of exposure to styrene, but this may have been due to chance. Mortalit...
متن کاملEpidemiologic studies of styrene and cancer: a review of the literature.
OBJECTIVE To review the epidemiologic literature on styrene and cancer. METHODS We reviewed studies of workers exposed to styrene in manufacturing and polymerization, in the reinforced plastics industry, and in styrene-butadiene rubber production. We also reviewed studies of workers monitored for styrene exposure, studies of environmental exposure, community-based case-control studies of lymp...
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